Pharmacy, Natural & Health Sciences

Pharmacy - Faculty Profiles

Shekher MohanShekher Mohan, Ph.D. 

Assistant Professor of Pharmaceutical Sciences
260-470-4057  
smohan@manchester.edu



 

Education

2004-2008        Ph.D., Biomedical Science - Neuropharmacology  
Oklahoma State Univ., Ctrn. for Health Sciences, College of Medicine, Tulsa, OK

1998-2002        B.Sc. (HONS) Life Science - Pharmacology                                                                     
Univ. of Hertfordshire, School of Life Sciences, Hatfield, Hertfordshire, England, UK

 

Work Experience

2017-present    Manchester University, Fort Wayne, IN                                                                                
Dept. of Pharmaceutical Sciences, College of Pharmacy, Natural & Health Sciences
Assistant Professor - Pharmacology

2014-2017        Marshall University, Huntington, WV                                                                                   
Dept. of Pharmaceutical Science & Research, School of Pharmacy
Assistant Professor  - Pharmacology  

Fall 2015           Marshall University, Huntington, WV                                                                                   
Dept. of Anatomy, School of Medicine
Adjunct Professor – Neuroanatomy

Spring 2014      Santa Fe College, Dept. For Health Programs, Gainesville, FL                              
Adjunct Professor - Anatomy & Physiology-II w/lab, undergraduate students

2010-2014        University of Florida, Gainesville, FL                                                                                   
Dept. of Anesthesiology, College of Medicine
National Research Service Award Recipient (NRSA) (NIH-NINDS) Postdoctoral Fellowship

2009-2010        University of Iowa, Iowa City, IA                                                                             
Dept. of Anesthesia, College of Medicine
Postdoctoral Research Scholar

2003-2008        Oklahoma State University, Tulsa, OK                                                                   
Dept. of Pharmacology & Physiology, College of Medicine
Graduate Student Assistant

2002-2003        Pfizer Inc., Sandwich, England, UK                                                                        
Sexual Health and Urology Discovery Program
Pharmacokinetic/Pharmacodynamics Ligand Research Assistant

Peer-Reviewed Publications

*corresponding author

  1. Stevens. S., (Ph.D. student) Flaugher. T., Hughes. K., Terrwilliger. C., Hicks. M., (P3 pharmacy students), *Mohan S. Gender Difference in Withdrawing Infants. Global Pediatric Health., March 2018(doi: 10.1177/2333794X18775886)
  2. *Mohan. S., Koller. J.E., Fazal A. F., De Oliveira G.A., Pawlowicz. I. A., (undergraduates), Dore. S. Genetic deletion of F2α-FP receptor exacerbates brain injury after experimental intracerebral hemorrhage. Frontiers Neuroscience. September 2018$ (doi: 10.3389/fnins.2018.00556)
  3. Stevens. S., (Ph.D. student) Heffner. C., Flaugher. T., (P3 pharmacy students), *Mohan. S. Neonatal Abstinence Syndrome (NAS): Neurodevelopmental Challenges, Current Management and Future Directions. Current Opinions in Neurological Science. M2017(https://scientiaricerca.com/srcons/SRCONS-01-00005.php)
  4.  Heffner. C., (P3 pharmacy student), *Mohan. S. New Drug Spotlight: Epilepsy. Cabell Huntington Hospital, Marshall University, Monthly Dose Newsletter, September, 2016
  5. *Mohan. S., Interleukin-1beta: a common thread between inflammation, pain and opioid tolerance. Neuroimmunology and Neuroinflammation, September 2016, (doi: 10.20517/2347-8659.2016.37)
  6. *Mohan. S., Robinson TJ., Armstrong L., (undergraduates), Allen N. (P3 pharmacy student), Stevens. S., (Ph.D. student). Morphine-mediated cytoprotection from hemin in SK-N-SH and A172 cells. Neurochemistry & Neuropharmacology. September 2016, (doi: 10.4172/2469-9780.1000113)
  7. Mohan. S., Dore. S. Neuroproective Role of Prostaglandin-EP2 receptor in hemin-mediated toxicity. NeuroToxicology. November, 2015, (doi: 10.1016/j.neuro.2014.10.012)
  8. Ameli P.A., Ameli N.J., Gubernick D.M., Ansari S., Mohan S., Buckley A. K., Maxwell C.W., Nayak V.H., Hedna V.S. The role of vasopressin and it antagonism in stroke related edema. J. Neurosci Res. 92(9): 1091-9, 2014 (doi: 10.1002/jnr.23407)
  9. Mohan. S., Glushakov. A.V., deCurnou A. (undergraduate), Dore. S. Contribution of PGE2 EP1 receptor in hemin-induced neurotoxicity. Frontiers in Mol. Neurosci. 6(31), 2013 (doi: 10.3389/fnmol.2013.00031)
  10. Mohan. S, Ahmad, A.S., Glushakov A.V., Chamber. C. (undergraduate), Dore. S. Putative role of prostaglandin receptor in intracerebral hemorrhage. Frontiers in Neurology 3(145), 2012 (doi: 10.3389/fneur.2012.00145)
  11. Mohan. S, Spofford C.M., Kang. S, Jang J.H. and Brennan T.J. Evaluation of
    Leukemia Inhibitory Factor in a rodent model of postoperative pain. (Front cover) J. Pain 12(7): 819-32, 2011 (doi: 10.1016/j.jpain.2011.02.351)
  12. Mohan S, Davis R.L., DeSilva U. and Stevens C.W. Dual regulation of mu-opioid receptors in SK-N-SH neuroblastoma cells by morphine and interleukin-1beta: evidence for opioid-immune crosstalk. J.Neuroimmol 227(1-2): 26-34, 2010 (doi: 10.1016/j.jneuroim.2010.06.007)
  13. Davis R.L., Buck D.J., Saffarian N, Mohan S, DeSilva U and Stevens C.W. β-Funaltrexamine inhibits inducible nitric-oxide synthase expression in human astroglial cells.  J. NeuroImmune Pharmacol. 3(3): 150-153, 2008 (doi: 10.1007/s11481-008-9102-x)
  14. Stevens C.W., Brasel C.M., and Mohan S. Cloning and bioinformatics of amphibian mu, delta, kappa and nociceptin opioid receptors expressed in brain tissue: Evidence for opioid receptor divergence in mammals. Neurosci. Lett. 419: 189-194, 2007
  15. Mohan. S., and Stevens C.W. Systemic and Spinal Administration of mu-opioid, Remifentanil produces antinociception in Amphibians. Eur. J. Pharmacol. 18; 534(1-3): 89-94, 2006

 

Published Abstracts (2015-2019)

  1. S. Stevens and S. Mohan ‘Assessing Physiological Behavioral Changes Following In Utero Opioid Exposure in Rodents’ Society For Neuroscience (SfN). October 2019
  2. S. Stevens and S. Mohan ‘Assessing Behavioral Changes Following In Utero Opioid Exposure in Rodents’ Manchester University, College of Pharmacy, Natural and Health Sciences, Celebrating Accomplishments . May 2019
  3. S. Stevens and S. Mohan ‘Assessing Behavioral Changes Following In Utero Opioid Exposure in Rodents’ Greater Indiana Chapter For Society For Neuroscience. April 2019
  4. S. Stevens and S. Mohan ‘Modeling opioid-mediated neonatal abstinence syndrome (NAS) to improve our understanding of challenges in neurodevelopment’. Society For Neuroscience (SfN). October 2017
  5. S. Stevens (graduate student), H. Isaacs (pharmacy student) H. Claar (pharmacy student) and S. Mohan ‘Role of interleukin-1 receptor (IL-1R) in morphine-induced hyperalgesia using a mouse model of postop., pain. Univ. of Kentucky - CCTS Spring Conference April 2017
  6. R. Moawad (pharmacy student), T. Flaugher (pharmacy student), R. Stevens (pharmacy student), T. Norzin (pharmacy student) and S. Mohan ‘Evaluation and Compliance of the Prescription Drug Monitoring Programs (PDMPs)’. ASHP Midyear Conference December 2016
  7. R. Johnson (pharmacy student), T. Flaugher (pharmacy student), T. Mills (pharmacy student), C. Terwilliger (pharmacy student) and S. Mohan ‘Is there differences in Finnegan scores between buprenorphine and polydrug exposed infants born with NAS in Cabell County, West Virginia’? ASHP Midyear Conference December 2016
  8. T. Mills (pharmacy student), T. Flaugher (pharmacy student), R. Johnson (pharmacy student), C. Terwilliger (pharmacy student) and S. Mohan ‘Are there gender related differences in infants born with NAS in Cabell County, West Virginia’? ASHP Midyear Conference December 2016
  9. T. Flaugher (pharmacy student), C. Terwilliger (pharmacy student), S. Stevens, L. Prunty PharmD BCPCS and S. Mohan ‘Symptomatic constitution of Finnegan scores for infants born in Cabell County, West Virginia and treated for NAS’. ASHP Midyear Conference December 2016
  10. N. Rockich-Winston M.S. Pharm.D., H. Koc Ph.D. and S. Mohan Ph.D. ‘Recommendation and implementation of an evaluation rubric for assessment of research IPPE and APPE rotations. AACP July 2016
  11. S. Stevens (graduate student) and S. Mohan ‘Role of interleukin-1 receptor (IL-1R) in morphine-induced hyperalgesia using a mouse model of postop., pain. Marshall Univ. School of Medicine, Annual Research Day March 2016
  12. H. Mick (undergraduate student) and S. Mohan ‘Role of opioids in hemin-induced neurotoxicity’. International Neurotoxicology Association (INA) Conference September 2015
  13. J. R Robsinson (undergraduate student) and S. Mohan ‘The role of morphine in hemin-mediated toxicity in neuronal, SK-N-SH cell-line’. 25thNeuropharmacology Conference October 2015
  14. H. Mick (undergraduate student) and S. Mohan ‘Role of opioids in hemin-induced neurotoxicity’. Marshall Univ. School of Medicine, Annual Research Day March 2015

 

Professional Hons and Awards

2016                  MuSoP - INCO Foundation Grant, Faculty Development, Awarded $400              

2015                  MuSoP - Nomination, Pickens Queen Young Teacher Award                                            

2015                  MuSoP - Quinlan Foundation, Travel Grant, Awarded $500                                  

2015 -’16           MuSoP - Awarded Course Coordinator of the Year (PHRM751, Class of 2017)                 

2014 - ’15          MuSoP - Awarded Teacher of the Year (PHRM751, Class of 2016)                      

2014 -’15           MuSoP - Awarded Course Team of the Year (PHRM544, Class of 2018)

2013                  Univ.,  of Florida - McKnight Brain Institute, Travel Grant, Awarded $1000

2001                  Awarded Study Abroad Research Scholarship                                          

1996                  Awarded “Most Work Ethic” Award (High School)                                                              

 

Professional Affiliations

  1. American Association of Pharmaceutical Scientist (AAPS)                                           
  2. American Association of Colleges of Pharmacy (AACP)                                                           
  3. Midwest Pain Society (MPS)                                                                                                     
  4. Society for Neuroscience (SfN)                                                                                                  
  5. American Society for Cell Biology (ASCB)                                                                    
  6. Neuropharmacology                                                                                                                  
  7. American Heart Association (AHA)                                                                               

 

Teaching Assignments:

Fall semester:

PHRM450 Introduction to Integrated Pharmacotherapy (P2)

PHRM451 Integrated Pharmacotherapy- neurology topics - pain, headache, epilepsy, AD, PD (P2)

PHRM552 Integrated Pharmacotherapy- pathophysiology and pharmacology of the renal & urological system (P3)

 

Spring semester:

PHRM454 Integrated Pharmacotherapy - psychiatry topics -  depression, anxiety, sleep, schizophrenia, bipolar, ADHD, addiction (P2)

PHRM311 BioMed. II - physiology, pathophysiology & pharmacology of the central nervous system and renal-kidney system (P1)

 

Research Projects

  1. Neonatal Abstinence Syndrome (NAS) – using a novel preclinical model to understand the short and long-term impact of opioid exposure in utero
  2. Perception and impact of substance use disorder (SUD) in the workplace
  3. Perception of students vs. faculty on the delivery of IPT courses at Manchester Univ., College of Pharmacy
  4. Prescription drug monitoring programs (PDMR’s) – utilization, barriers, effectiveness and impact in substance use disorders (SUD’s)