Pharmacy, Natural & Health Sciences

Pharmacogenomics

Master of Science in Pharmacogenomics: Curriculum - Online Degree Program Beginning in Summer 2018

(or see traditional onsite program)

 

Online Clinical Track
40 Credits of Online Education

Semester 1 – Summer 2018

Course nameCourse descriptionCredit hours
Introduction to Pharmacogenomics(PGx 501)A presentation of the evolution of pharmacogenetics/pharmacogenomics, the human genome and modern applications of DNA information related to drugs. There will also be focused attention to necessary calculations for research and an introduction to pharmacokinetics.

2

Human Genetics(PGx 521)Discusses how genes influence human traits, diseases, and behaviors, including how non-genetic factors interact with genetic factors to produce observable phenotypes. Human inheritance patterns, genome organization, linkage, and medical applications of genetics in the diagnosis, treatment, and prevention of disease will be explored.

4

Semester 2 – Fall 2018

Course nameCourse description

Credit hours

Bioinformatics(PGx 531)Introduction and exploration of the computational and informational aspects of genomics and proteomics. Includes aspects of sequence similarity analysis, sequence similarity searches, pair-wise analysis, phylogenic trees (and relevance to human genomics), allelic variation analysis, user interface in health care management, population genetics, genomics data results analysis, data quality, and predictions and confirmations of genomics-based altered drug responses.

4

Advanced Pharmacokinetics(PGx 512)Discusses the mathematical and conceptual study of the time course of drug absorption, distribution, metabolism, and excretion.

2

Semester 3 – Spring 2019

Course nameCourse description

Credit hours

Pharmacology(PGx 510)Discusses the cellular and molecular mechanisms of drug action, studied within the disciplines of neuropharmacology and cardiovascular pharmacology, endocrine pharmacology, antimicrobials, and cancer pharmacology. Included are lectures on basic physiology that underlie the mechanisms of important pharmacological agents. Special topics include drug discovery, new uses for established drugs, and pharmacogenetic/pharmacogenomic effects.

4

Data Analysis/Biostatistics(PGx 533)Discusses the use of statistical methods to process public health and genetic data. An emphasis on interpretation and concepts in areas such as population genetics, genome-wide association studies and systems biology will be undertaken.

3

Semester 4 – Summer 2019

Course nameCourse description

Credit hours

Applied Pharmacogenomics 1(PGx 526)Discusses single nucleotide polymorphisms and other genetic variations and their potential impact on clinical medicine and related clinical outcomes. The translation of genetic variations to drug selection, dosing regimens, adverse effects, and regimen optimization will be discussed.

3

Advanced Molecular Biology(PGx 511)Concepts will be related to analytical methodology. Current approaches to DNA manipulation and mutation analysis, protein assays, quantitative analysis of gene expression, sequencing, immunostaining, microscopy, and image analysis will be discussed.

3

Research Responsibility and Ethics(PGx 515)Discusses ethics of scientific research involving humans. Bioethics and how it is applied to design and conduct of human drug research. Ethical issues involved with personal genetic information will be emphasized.

1

Semester 5 – Fall 2019

Course nameCourse description

Credit hours

Patient Genome Evaluation I(PGx 519)Longitudinal project, investigating the genome of a patient.

2

Applied Pharmacogenomics 2(PGx 536)A continuation of Applied Pharmacogenomics and will continue to focus on single nucleotide polymorphisms and other genetic variation and their potential impact on clinical medicine and related clinical outcomes. The translation of genetic variations to drug selection, dosing regimens, adverse effects, and regimen optimization will be discussed.

3

Pharmacogenomics in Practice 1(PGx 5XX)A two-part course focused in application of pharmacogenomics in a practice setting. The course will include onsite practicums, and write-ups and discussions of complicated patient cases that are produced by the student. The course will also include the composition of a business plan or implementation plan for introducing pharmacogenomics into the practice of the practicum site.

3

Semester 6 – Spring 2020

Course nameCourse description

Credit hours

Pharmacogenomics in Practice 2(PGx 5XX)Continuation of Pharmacogenomics in Practice I

2

Patient Genome Evaluation II(PGx 529)Continuation of Patient Genome Evaluation I, cumulating in a student presentations.

4

Total Credit Hours

40